Creamy Baked Chicken Alfredo Casserole

Featured in: Simple Family Plates

This creamy baked casserole combines tender chicken breast, al dente pasta, and a luxurious Alfredo sauce made with butter, garlic, heavy cream, and Parmesan cheese, topped with melted mozzarella for an irresistible finish.

Perfect for family dinners, this Italian-American classic comes together in under an hour with simple ingredients and straightforward techniques. The buttery garlic cream sauce coats every bite, while the baked mozzarella topping creates a golden, bubbling layer that adds textural contrast and richness.

Updated on Sun, 18 Jan 2026 12:04:00 GMT
Golden-brown Chicken Alfredo Casserole fresh from the oven, featuring creamy sauce, tender chicken, and bubbly mozzarella.  Save to Pinterest
Golden-brown Chicken Alfredo Casserole fresh from the oven, featuring creamy sauce, tender chicken, and bubbly mozzarella. | aksilkitchen.com

My daughter used to wrinkle her nose at anything green on her plate, so I needed a dish that could hide vegetables while still feeling indulgent. This casserole became my solution on a particularly frantic Tuesday when I had leftover rotisserie chicken and a craving for something warm and cheesy. The smell of garlic butter hitting the pan pulled everyone into the kitchen before I even called them. I watched the cream thicken into silk, and when I pulled that bubbling, golden dish from the oven, even the pickiest eater asked for seconds. It's been my secret weapon ever since.

I made this for my book club once, and the room went quiet in the best way possible. Someone finally said it tasted like the kind of comfort food you dream about on cold nights. I'd tucked spinach into the sauce that time, and no one noticed until I mentioned it later. The laughter that followed, mixed with requests for the recipe, made me realize this dish has a way of bringing people together without any fuss.

Ingredients

  • Penne or ziti pasta: These shapes have ridges and tubes that trap the Alfredo sauce perfectly, so every bite is creamy and satisfying.
  • Cooked chicken breast: I always use rotisserie chicken when I'm short on time, the flavor is already there and it shreds beautifully into the sauce.
  • Unsalted butter: This is the base of your sauce, and using unsalted lets you control the seasoning without it getting too salty.
  • Garlic: Fresh garlic releases a fragrance that makes the whole house smell like an Italian kitchen, don't skip the quick saute.
  • Heavy cream: The richness here is what makes the sauce luxurious and thick, it coats the pasta like a warm hug.
  • Freshly grated Parmesan cheese: Pre-grated just doesn't melt the same way, freshly grated Parmesan gives you that smooth, velvety texture.
  • Salt, black pepper, and nutmeg: Nutmeg is optional but adds a subtle warmth that makes people ask what your secret is.
  • Shredded mozzarella cheese: This melts into gooey, golden perfection on top and creates those crispy bits everyone fights over.
  • Fresh parsley: A sprinkle at the end brightens the richness and makes it look like you really know what you're doing.

Instructions

Product image
Make fresh homemade yogurt and fermented foods easily for breakfasts, snacks, and recipes.
Check price on Amazon
Prep the oven and dish:
Set your oven to 375°F and grease a 9x13-inch baking dish so nothing sticks. This step takes seconds but saves you scrubbing later.
Boil the pasta:
Cook your penne or ziti in salted water until it's just al dente, it'll finish cooking in the oven. Drain it well and set it aside while you make the magic happen.
Start the Alfredo sauce:
Melt butter in a large saucepan over medium heat, then toss in the minced garlic and let it sizzle for about a minute. The smell will tell you when it's ready, fragrant but not brown.
Build the creamy base:
Pour in the heavy cream and bring it to a gentle simmer, then stir in the Parmesan, salt, pepper, and nutmeg if you're using it. Keep stirring until the cheese melts and the sauce turns smooth and glossy.
Combine everything:
Add the cooked chicken and drained pasta to the sauce, stirring until every piece is coated. It should look rich and cohesive, like everything belongs together.
Assemble the casserole:
Pour the mixture into your prepared baking dish and spread it evenly, then blanket the top with shredded mozzarella. Don't be shy with the cheese, it's the best part.
Bake until golden:
Slide the dish into the oven and bake for 25 to 30 minutes, until the cheese is bubbling and turning golden brown in spots. The edges will get a little crispy, and that's exactly what you want.
Rest and serve:
Let the casserole sit for 5 minutes before serving so the sauce can settle. Sprinkle fresh parsley on top if you have it, then dig in.
Product image
Make fresh homemade yogurt and fermented foods easily for breakfasts, snacks, and recipes.
Check price on Amazon
A close-up of Chicken Alfredo Casserole in a baking dish, garnished with fresh parsley for a family meal.  Save to Pinterest
A close-up of Chicken Alfredo Casserole in a baking dish, garnished with fresh parsley for a family meal. | aksilkitchen.com

One winter evening, I served this to my in-laws who are notoriously hard to impress. My father-in-law, a man of few words, asked if there was more before he even finished his first serving. My mother-in-law leaned over and whispered that it reminded her of a dish her own mother used to make, and I saw her eyes get a little misty. That's when I knew this casserole was more than just dinner.

Making It Your Own

I've tucked steamed broccoli florets into the sauce before baking, and suddenly it felt a little less guilty. Sauteed mushrooms add an earthy depth, and fresh spinach wilts right into the cream without anyone noticing. If you want a lighter version, swap the heavy cream for half-and-half, it's still creamy but won't weigh you down. Sometimes I'll toss in a pinch of red pepper flakes for a tiny kick that surprises people in the best way.

What to Serve Alongside

A crisp green salad with a tangy vinaigrette cuts through the richness and makes the meal feel balanced. I like to throw together arugula, cherry tomatoes, and a squeeze of lemon for something bright and fresh. Garlic bread is always a hit, but honestly, this casserole is hearty enough to stand alone. A glass of chilled Chardonnay rounds out the experience, especially if you're pretending it's a fancy dinner party.

Storage and Reheating

Leftovers keep in the fridge for up to three days in an airtight container, and they reheat beautifully in the oven or microwave. I actually think the flavors deepen overnight, like the sauce and pasta have time to really get to know each other. You can also assemble the whole casserole a day ahead, cover it tightly, and bake it fresh when you need it.

  • Cover with foil for the first half of reheating to keep the top from drying out.
  • Add a splash of milk or cream when reheating to bring back that silky texture.
  • Freeze assembled casseroles for up to two months, just thaw in the fridge overnight before baking.
Product image
Juice whole fruits and vegetables easily for fresh drinks, sauces, and nutrient-rich recipes.
Check price on Amazon
Serving spoon lifting a portion of Chicken Alfredo Casserole, revealing gooey cheese and hearty penne pasta inside. Save to Pinterest
Serving spoon lifting a portion of Chicken Alfredo Casserole, revealing gooey cheese and hearty penne pasta inside. | aksilkitchen.com

This casserole has become the dish I make when I want to show someone I care without making a big deal about it. It's warm, filling, and always tastes like home.

Recipe Questions & Answers

Can I prepare this casserole in advance?

Yes, you can assemble the casserole up to 24 hours ahead. Cover with foil and refrigerate. Add 10-15 minutes to baking time if baking from cold.

What type of pasta works best?

Penne and ziti are ideal because their shape holds the creamy sauce well. Short, tubular pastas work better than long strands for even coating and texture.

How do I prevent the sauce from becoming too thick?

Cook the cream over medium-low heat and avoid boiling. If the sauce thickens too much, whisk in a splash of pasta water or additional cream to reach desired consistency.

Can I make this with a lighter sauce?

Absolutely. Replace heavy cream with half-and-half or a combination of milk and cream. The casserole will be lighter but still creamy and delicious.

What vegetables pair well with this dish?

Steamed broccoli, spinach, sautéed mushrooms, or sun-dried tomatoes complement the creamy sauce beautifully. Stir them in before baking for integrated flavors.

How long can leftovers keep?

Store covered in the refrigerator for up to 3 days. Reheat gently in a 325°F oven until warmed through, covering with foil to prevent drying.

Creamy Baked Chicken Alfredo Casserole

Rich and creamy baked pasta with tender chicken, silky Alfredo sauce, and gooey mozzarella cheese.

Prep Time
20 minutes
Time to Cook
30 minutes
Overall Prep Time
50 minutes
Recipe by Marcus Ridge


Skill Level Easy

Cuisine Italian-American

Makes 6 Portions

Dietary Details None specified

What You'll Need

Pasta

01 12 oz penne or ziti pasta

Chicken

01 2 cups cooked chicken breast, diced or shredded

Sauce

01 2 tablespoons unsalted butter
02 3 cloves garlic, minced
03 2 cups heavy cream
04 1 cup freshly grated Parmesan cheese
05 1/2 teaspoon salt
06 1/4 teaspoon freshly ground black pepper
07 1/4 teaspoon ground nutmeg

Cheese Topping

01 2 cups shredded mozzarella cheese

Garnish

01 2 tablespoons fresh parsley, chopped

How to Prepare

Step 01

Prepare baking dish: Preheat oven to 375°F. Grease a 9x13-inch baking dish and set aside.

Step 02

Cook pasta: Cook pasta in salted boiling water until al dente. Drain thoroughly and set aside.

Step 03

Create Alfredo base: Melt butter in a large saucepan over medium heat. Add minced garlic and sauté for 1 minute until fragrant.

Step 04

Develop sauce: Pour in heavy cream and bring to a gentle simmer. Add Parmesan cheese, salt, pepper, and nutmeg. Stir continuously until cheese melts and sauce achieves smooth consistency.

Step 05

Combine components: Add cooked chicken and drained pasta to the Alfredo sauce. Mix thoroughly to ensure even coating of all ingredients.

Step 06

Assemble casserole: Transfer mixture into prepared baking dish. Distribute shredded mozzarella evenly across the top.

Step 07

Bake casserole: Bake for 25 to 30 minutes until mozzarella is bubbling and golden brown on top.

Step 08

Rest and serve: Allow casserole to stand for 5 minutes before serving. Garnish with fresh parsley if desired.

Tools You'll Need

  • Large pot
  • Saucepan
  • 9x13-inch baking dish
  • Mixing spoons
  • Colander

Allergy Warnings

Review all ingredients to find possible allergens and consult a medical expert for concerns.
  • Contains milk and dairy products
  • Contains wheat and gluten
  • May contain egg if using egg-based pasta

Nutrition Data (Per Serving)

Use these nutrition details for guidance only—they aren't a substitute for your doctor's advice.
  • Energy: 540
  • Fats: 28 g
  • Carbohydrates: 39 g
  • Proteins: 32 g